Trimethyl Chitosan forms gels with multivalent anions and clear solutions that dry to strong, clear films. Its ideal for scaffolds, cell therapy, drug delivery, and biomedical applications. Its a water soluble natural biopolymer that’s biocompatible, biodegradable, antibacterial, and adhesive to tissue.

Quaternization of chitosan is a method of modifying and improving the properties and functionalities of chitosan.  Quaternization of chitosan occurs by introducing a quaternary ammonium moiety onto or outside the chitosan backbone, via chemical reactions with primary amino and hydroxyl groups. The most established form of quaternized chitosan is N,N,N-trimethyl chitosan (TMC) and N-[(2-hydroxy-3-trimethyl ammonium) propyl] chitosan. By modifying chitosan through the insertion of a quaternary moiety, permanent cationic charges on the polysaccharide backbone results in improvements in many of chitosan’s beneficial properties, such as improved;

• Aqueous (water) solubility
• High charge density and positive charge
• Stability over a wide pH and ionic conditions
• Mucoadhesion
• Permeation (ability to open and cross tight junctions of epithelial cells)
• Penetration of drugs and therapeutics
• Antimicrobial activity

These Trimethyl Chitosan properties broaden chitosan’s applicability across a vast array of biomedical and pharmaceutical applications.

• Drug Delivery
• Vaccine Adjuvant
• Tissue Engineering
• Haemostat
• Biomedical devices
• Drug delivery facilitator
• Wound-healing
• Micro and Nanoparticle encapsulation for controlled release in drug delivery and other therapeutics
• Scaffolding tissue engineering and regeneration
• Pharmaceutical excipient
• Cosmetics
• Anti-microbial, fertilizer, and growth elicitor for plants
• Food preservation
• Dietary supplement